In the mid-1800s, two groups of faithful women, dedicated to caring for the poor and sick, journeyed to a booming riverfront town in Ohio. The Franciscan Sisters of the Poor missionaries from Germany created the beginnings of a hospital in Over-the-Rhine, while the Sisters of Mercy group that sailed from Ireland established a hospital in Hamilton.

In 1999, the two organizations joined to form Mercy Health Partners of Southwest Ohio, the second-largest hospital and healthcare system in Greater Cincinnati.

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